IRCCS Saverio De Bellis

Direttore Scientifico

Prof. Gianluigi Giannelli

The National Institute of Research in Gastroenterology “Saverio de Bellis” is a hospital and research center specialized in clinical and surgical gastroenterology. The Institute is certified by the Italian Ministry of Health as one of the national IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico).

The IRCCS “Saverio de Bellis” is a part of the Health System of the Apulia Region, where it performs high-level functions in terms of health care, research and training activities.

In the regional network, as a center of excellence, the role of the IRCCS “Saverio de Bellis” is to address surgical gastroenterology, endoscopic and hepatological gastroenterology as well as experimentation in the hepatocellular and nutritional field.  It has recently become a regional reference center for acute, chronic and neoplastic diseases of the digestive tract and, in the most recent years, for metabolic and dietary diseases.

The numbers of health services carried out at the center are constantly increasing; last year about 10 thousand endoscopic examinations were recorded, about 3 thousand of which were interventional, over 1,200 gastroenteric surgery procedures, and 2,000 new patients per year are followed up at the nutritional clinic. The proposed care model is particularly important, whereby patient management is handled by a multidisciplinary team, consisting of a gastroenterologist, surgeon, endoscopist, nutritionist and nutritional physiopathologist, oncologist, radiologist, anatomist pathologist, geneticist, pharmacologist and epidemiologist. This offers a unique diagnostic-therapeutic path in gastroenterology, supported by transverse platforms that guarantee a high added value, such as the laboratory of nutraceutical and personalized medicine, but also the telemedicine facility that has now been implemented, which allows home telemonitoring, with the ultimate goal of promoting patient and family members empowerment and improving their quality of life.

The IRCCS “Saverio de Bellis” is an important and advanced research structure, which covers about 1,200 square meters of laboratories specifically dedicated to research, about 570 square meters of dedicated health care services and an animal facility covering about 220 square meters.

The research lines follow the 3-p model: precision, preventive/predictive, participatory.

Research at the IRCCS “Saverio de Bellis” is translational and has results with direct, positive repercussions on health care and the public. In fact, a series of innovative genetic tests are available to identify the most suitable biological therapy to fight already diagnosed tumors (“targeted therapy”) or to investigate the predisposition to new mutations in the patient’s family members.


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