Oncohematology
Always a frontier in genomic and/or personalized medicine
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Secretary
Enrico Derenzini
IEO MILANO
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Clinical Coordinator
Fabio Ciceri
HSR MILANO
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Pre Clinical Coordinator
Giorgia Simonetti
IRST MELDOLA
The ACC Oncohaematology Working Group has two main objectives for the next three years. The diseases that will be the main focus are aggressive B-cell lymphomas and acute myeloid leukemias.
The WG is coordinated by Enrico Derenzini (IEO) and is composed of 18 sites.
The first objective is to build a ‘hi-tech’ diagnostic network that can be a reference platform for implementing innovative clinical trials in the field of aggressive lymphomas and acute myeloid leukemia.
The second objective is a study aimed at “multi-omics” (genomics, proteomics and metabolic) characterization of leukemias and lymphomas with alterations of the TP53 gene. Alterations of this gene profoundly impact the biology of these tumour, leading to resistance to current therapies and extensive metabolic reprogramming. This study aims to identify any vulnerabilities linked to TP53 gene dysfunction with a functional characterization approach that goes beyond genomics, to set up, for both pathologies, innovative therapies based on the concept of “synthetic lethality”.
The innovative structure of the WG will allow the various IRCCS adhering to insert their projects within the ACC network progressively.
Team
- Pre-Clinics
- Clinicians
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IRE ROMA
Maurizio Fanciulli
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AUSL IRCCS
Benedetta Donati
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ONCOLOGICO BARI
Sabino Ciavarella
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CRO AVIANO
Valter Gattei
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PASCALE NAPOLI
Stefania Crisci
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IRCCS GEMELLI ROMA
Stefan Hohaus
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CSS S.G. ROTONDO
Vincenzo Giambra
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IRCCS SAN RAFFAELE MI
Luca Vago
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IRCCS GASLINI
Marina Lanciotti
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IEO MILANO
Stefano Pileri
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IRST MELDOLA
Giorgia Simonetti
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IOV PADOVA
Eric Piovan
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IRCCS CROB
Fiorella D’Auria, Antonella Caivano
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FPO CANDIOLO
Alberto Pisacane
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INT MILANO
Cristiana Carniti
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OPBG ROMA
Concetta Quintarelli
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OSP. POL. S. MARTINO GENOVA
Franco Fais
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IRCCS CROB
Fiorella D'Auria
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IRCCS CROB
Antonella Caivano
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IRCCS AOU BOLOGNA
Elena Sabattini
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IRE ROMA
Francesco Marchesi
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IRCCS HUMANITAS
Armando Santoro
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AUSL IRCCS
Stefano Luminari
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ONCOLOGICO BARI
Attilio Guarini
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PASCALE NAPOLI
Antonello Pinto
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IRCCS GEMELLI ROMA
Luciana Teofili, Patrizia Chiusolo
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CSS S.G. ROTONDO
Giovanni Rossi
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IEO MILANO
Enrico Derenzini, Corrado Tarella
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IRCCS GASLINI
Carlo Dufour
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IRST MELDOLA
Gerardo Musuraca
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IOV PADOVA
Michele Gottardi
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IRCCS CROB
Giuseppe Pietrantuono
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FPO CANDIOLO
Fabrizio Carnevale
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CRO AVIANO
Michele Spina
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OSR MILANO
Fabio Ciceri
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INT MILANO
Paolo Corradini
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OPBG ROMA
Mattia Algeri
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OSP. POL. S. MARTINO GENOVA
Roberto Lemoli
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IRCCS FOND. S. MATTEO PAVIA
Luca Arcaini
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IRCCS SAN RAFFAELE MI
Fabio Ciceri
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IRCCS SDN
Giovanni Smaldone
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IRCCS AOU BOLOGNA
Pier Luigi Zinzani